PowerPoint's biggest downfall is the people that use it. It can be a great tool for giving a speech, but most people use it as a crutch and read directly from it rather than using it to convey talking points. It also works better with certain audiences (upper management) than it does with individual contributors.
On my last trip to China I opened my 2-day meeting agenda with one simple statement: "I didn't bring a single PowerPoint presentation with me". You'd think I promised them I'd make the government stop blocking access to porn online.